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Vitamin B12 Deficiency: Pernicious Anemia
You may have heard of people who have to get vitamin B12 shots because of a condition called pernicious anemia. What is this, how is it different from other anemia, and what are the symptoms?
Pernicious anemia is a deficiency of the B12 vitamin. Vitamins do not provide nutrition to the body on their own, rather they work with food or other elements in the body such as bacterias and enzymes to help the body work properly. Their absorption is also affected by other substances in the body, some that are already there, and some that people may ingest. In order to absorb vitamin B12, the body uses a substance called intrinsic factor, which is produced by the stomach. Some people’s bodies either do not produce intrinsic factor at all, or they do not produce enough to effectively process vitamin B12 taken through food sources (like milk) or oral supplements. Older people may suffer from pernicious anemia even if they did not have it earlier in life, because as we age, our bodies produce less intrinsic factor. Also, more women than men suffer from it. People with pernicious anemia have to receive B12 by injection, because this form does not require combination with intrinsic factor to be absorbed by the body. People can also suffer from B12 deficiency unrelated to intrinsic factor problems, and this is called macrocytic anemia. It can be caused by poor diet, alcoholism, or metabolic disorders.
Symptoms of pernicious anemia include fatigue, diarrhea, rapid heart rate, and shortness of breath. While these symptoms fit a large range of maladies, people with pernicious anemia may also exhibit the Babinski reflex. When you stroke the bottom of the foot, the big toe flexes up and the other toes fan out. It is a reflex present in newborns and usually disappears by the age of 2, as the nervous system matures. When the reflex exists in older people, it can be a sign of nerve damage. It can be inherited, and is rarely diagnosed until age 30. All anemia is characterized by lower than normal numbers of red blood cells. There are several different types of anemia with different causes. Common anemias you may be familiar with are anemia caused by iron deficiency, and sickle cell anemia, where red blood cells are sickle, or crescent moon shaped and can stick together, causing fatigue and other symptoms. In pernicious anemia, patients have a low red blood cell count, but the red blood cells they do have are abnormally large, and their white blood cells have abnormally large nuclei. Further tests for antibodies against intrinsic factor can be performed to make a diagnosis of pernicious anemia.
News Jobs & Trends .Calgary
Calgary |
Steve Spott named head coach of Canada's junior teamCalgary HeraldCALGARY ? Steve Spott will be Canada's head coach at the next world junior hockey championships. Spott, head coach and GM of the Kitchener Rangers, will have Mario Duhamel, Don Nachbaur and Andre Tourigny as his assistants for the Dec. 26-Jan.and more » |
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Home hit by gunshots was targeted, police suspectCBC.caCalgary police are investigating what they believe was a targeted shooting directed at a northeast home. Gun fire, that managed to hit a couch in the home, was reported in Monterey Park just before 11 pm MT Friday, police said. No one was injured.and more » |
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Steve Spott named head coach of Canada's junior teamThe ProvinceCALGARY ? Steve Spott will be Canada's head coach at the next world junior hockey championships. Spott, head coach and GM of the Kitchener Rangers, will have Mario Duhamel, Don Nachbaur and Andre Tourigny as his assistants for the Dec. 26-Jan.and more » |
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Calgary teammates commit to Acadia women's soccerKings County Register/AdvertiserAcadia Varsity Athletics announced May 15 that Calgary teammates Michelle Pryde and Kayla Barry have committed to attend Acadia and join the Axewomen soccer program, starting this September. Pryde, a centre midfielder, and Barry, who has played both ... |
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Steve Spott named head coach of Canada's junior teamVictoria Times ColonistCALGARY ? Steve Spott will be Canada's head coach at the next world junior hockey championships. Spott, head coach and GM of the Kitchener Rangers, will have Mario Duhamel, Don Nachbaur and Andre Tourigny as his assistants for the Dec. 26-Jan.and more » |
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Steve Spott named head coach of Canada's junior teamStarPhoenixCALGARY ? Steve Spott will be Canada's head coach at the next world junior hockey championships. Spott, head coach and GM of the Kitchener Rangers, will have Mario Duhamel, Don Nachbaur and Andre Tourigny as his assistants for the Dec. 26-Jan.and more » |
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Steve Spott named head coach of Canada's junior teamCanada.comCALGARY ? Steve Spott will be Canada's head coach at the next world junior hockey championships. Spott, head coach and GM of the Kitchener Rangers, will have Mario Duhamel, Don Nachbaur and Andre Tourigny as his assistants for the Dec. 26-Jan.and more » |
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Calgary teammates commit to Acadia women's soccerNova News NowAcadia Varsity Athletics announced May 15 that Calgary teammates Michelle Pryde and Kayla Barry have committed to attend Acadia and join the Axewomen soccer program, starting this September. Pryde, a centre midfielder, and Barry, who has played both ...and more » |
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Seaway Crude Oil Pipeline Begins First FlowMarketWatch (press release)HOUSTON & CALGARY, Alberta, May 19, 2012 (BUSINESS WIRE) -- Enterprise Products Partners LP (NYSE:EPD) and Enbridge Inc. (nyse/tsx:ENB) announced that the Seaway Pipeline began accepting crude oil today at Cushing, Oklahoma for delivery to the US Gulf ...and more » |
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Keep it at homeCalgary HeraldRe: "Lines are necessary," Letter, May 17. As long as the power generated is used in Alberta, fair enough. The minute the power companies start exporting it, they should reimburse the citizens for the cost of the construction and maintenance. |
CTV.ca |
Gardeners get out their green thumbCTV.caMost people in Calgary agree that this is the first safe chance to get those flowers into the garden. While there is never a guarantee there won't be more frost or snow, the May long weekend is typically the time when that risk is manageable.and more » |
Globe and Mail |
The giant killer: Inside CP's overthrowGlobe and MailIt was not until after his jet touched down in Calgary's airport late Wednesday night that Bill Ackman got the signal he had been waiting months for: Canadian Pacific Railway Ltd. CP-T had hoisted the white flag. Lawyers for CP had just tabled an 11th ...and more » |
CTV.ca |
Gardeners get our their green thumbCTV.caMost people in Calgary agree that this is the first safe chance to get those flowers into the garden. While there is never a guarantee there won't be more frost or snow, the May long weekend is typically the time when that risk is manageable.and more » |
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Ackman Sends Wake-Up Call to Sleepy BoardroomsHamilton SpectatorMONTREAL William Ackman's triumph at Canadian Pacific Railway may echo across boardrooms far from the railroad's Calgary headquarters. In a Canadian corporate culture long resistant to activist shareholders, the US hedge-fund manager sounded a rousing ...and more » |
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Off-the-shelf solar systems ease hassles of going greenEdmonton JournalEnmax says Calgary is a leader at shredding red tape ? it takes as little as 24 hours to get your solar permits. Mark Harrison of the City of Edmonton says it takes anywhere from ?two days to a week? in the capital. And Wayne Perehudoff of the City of ...and more » |
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Pershing shakes the foundations of Canada's boardroomsMontreal GazetteWhile the event itself was entirely anticlimactic, after CP's chief executive, Fred Green, resigned less than three hours beforehand and the other five directors Pershing CEO Bill Ackman wanted replaced announced they would not stand for re-election, ...and more » |
Green Business News
Globe and Mail |
The giant killer: Inside CP's overthrowGlobe and MailIt was not until after his jet touched down in Calgary's airport late Wednesday night that Bill Ackman got the signal he had been waiting months for: Canadian Pacific Railway Ltd. CP-T had hoisted the white flag. Lawyers for CP had just tabled an 11th ...and more » |
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Ackman Sends Wake-Up Call to Sleepy BoardroomsHamilton SpectatorMONTREAL William Ackman's triumph at Canadian Pacific Railway may echo across boardrooms far from the railroad's Calgary headquarters. In a Canadian corporate culture long resistant to activist shareholders, the US hedge-fund manager sounded a rousing ...and more » |
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CP Rail's next move: Finding the right CEOToronto StarVanessa Lu Business Reporter CALGARY?With the bitter proxy battle behind them, the focus now shifts to who can put CP Rail on the right track. The new board of directors, which includes seven directors from activist investor Bill Ackman's slate, ...and more » |
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CP begins search for new CEOTheChronicleHerald.caCALGARY ? The search for a new boss at Canadian Pacific Railway Ltd. is underway after an activist hedge fund succeeded in its months-long battle to oust CEO Fred Green, a 34-year veteran of the railroad. Green, chairman John Cleghorn and four other ...and more » |
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Ackman Sends Wake-Up Call to Sleepy Canada BoardroomsBusinessWeekBy Frederic Tomesco on May 18, 2012 William Ackman's triumph at Canadian Pacific Railway Ltd. (CP) may echo across boardrooms far from the railroad's Calgary headquarters. In a Canadian corporate culture long resistant to activist shareholders, ...and more » |
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Candidates for CP boardCalgary HeraldCP has proposed the following directors: John Cleghorn, the current board chairman and former CEO of the Royal Bank of Canada; Tim Faithfull, former CEO of Shell Canada Ltd.; Rick George, the recently retired CEO of Suncor Energy Inc.; Fred Green, ...and more » |
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